Review





Similar Products

anti mixed lineage kinase domain like protein  (Cell Signaling Technology Inc)
86
Cell Signaling Technology Inc anti mixed lineage kinase domain like protein
Anti Mixed Lineage Kinase Domain Like Protein, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/protein+kinase+domain/pm41612193-113-24-31
Average 86 stars, based on 1 article reviews
anti mixed lineage kinase domain like protein - by Bioz Stars, 2026-09
86/100 stars
  Buy from Supplier
mixed lineage kinase domain like protein mlkl polyclonal antibody 178  (Proteintech)
96
Proteintech mixed lineage kinase domain like protein mlkl polyclonal antibody 178
Mixed Lineage Kinase Domain Like Protein Mlkl Polyclonal Antibody 178, supplied by Proteintech, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/protein+kinase+domain/MLKL+Antibody/pm41534751-77-110-119
Average 96 stars, based on 1 article reviews
mixed lineage kinase domain like protein mlkl polyclonal antibody 178 - by Bioz Stars, 2026-09
96/100 stars
  Buy from Supplier
anti phospho p mixed lineage kinase domain like protein mlkl  (Cell Signaling Technology Inc)
96
Cell Signaling Technology Inc anti phospho p mixed lineage kinase domain like protein mlkl
Anti Phospho P Mixed Lineage Kinase Domain Like Protein Mlkl, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/protein+kinase+domain/Phospho-MLKL+(Ser345)+Rabbit+mAb/10__4103_slash_nrr__nrr___d___25___00544-66-42-53
Average 96 stars, based on 1 article reviews
anti phospho p mixed lineage kinase domain like protein mlkl - by Bioz Stars, 2026-09
96/100 stars
  Buy from Supplier
mixed lineage kinase domain like protein mlkl  (Cell Signaling Technology Inc)
96
Cell Signaling Technology Inc mixed lineage kinase domain like protein mlkl
SNORD93 inhibited the proliferation of CRC. (A,B) Comparison of the effect of SNORD93 -overexpression vector and control pGPU6-NC vector on the cell cycle of CRC cell lines via flow cytometry (HCT-15: P=0.001; HT-29: P=0.048). (C) Western blot profiling of cell cycle regulators in SNORD93 -overexpressing CRC cells (HCT-15, p21 Waf1/Cip1: P=0.004; cyclin E2: P=0.047; cyclin D3: P=0.04; CDK9: P=0.03) (HT-29, p21 Waf1/Cip1: P=0.007; cyclin E2: P=0.008; cyclin D3: P=0.03; CDK9: P=0.01). (D) Comparison of the effect of the SNORD93 -overexpression vector and the control pGPU6-NC vector on apoptosis in CRC cell lines via flow cytometry. (E) Western blot profiling of apoptosis markers in SNORD93 -overexpressing CRC cells (HCT-15, caspase 8: P=0.044; caspase 3: P=0.044; caspase 7: P=0.006; Bim: P=0.01) (HT-29, caspase 8: P=0.01; caspase 3: P=0.02; caspase 7: P=0.008; Bim: P=0.002). (F) Western blot profiling of necroptosis markers in SNORD93 -overexpressing CRC cells <t>(HCT-15,</t> <t>p-RIP:</t> P=0.02; RIP: P=0.97; <t>p-MLKL:</t> P=0.04; MLKL: P=0.27) (HT-29, p-RIP: P=0.04; RIP: P=0.14; p-MLKL: P=0.01; MLKL: P=0.16). Data are presented as mean ± SD (n=3). ns, P>0.05; *, P<0.05; **, P<0.01. CRC, colorectal cancer; MLKL, mixed lineage kinase domain-like protein; NC, negative control; p-MLKL, phosphorylated MLKL; p-RIP, phosphorylated RIP; PI, propidium iodide; RIP, receptor-interacting protein; SD, standard deviation.
Mixed Lineage Kinase Domain Like Protein Mlkl, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/protein+kinase+domain/MLKL+Rabbit+mAb/pmc12554490-93-102-111
Average 96 stars, based on 1 article reviews
mixed lineage kinase domain like protein mlkl - by Bioz Stars, 2026-09
96/100 stars
  Buy from Supplier
phosphorylated mixed lineage kinase domain like protein p mlkl antibodies  (Affinity Biosciences)
86
Affinity Biosciences phosphorylated mixed lineage kinase domain like protein p mlkl antibodies
SNORD93 inhibited the proliferation of CRC. (A,B) Comparison of the effect of SNORD93 -overexpression vector and control pGPU6-NC vector on the cell cycle of CRC cell lines via flow cytometry (HCT-15: P=0.001; HT-29: P=0.048). (C) Western blot profiling of cell cycle regulators in SNORD93 -overexpressing CRC cells (HCT-15, p21 Waf1/Cip1: P=0.004; cyclin E2: P=0.047; cyclin D3: P=0.04; CDK9: P=0.03) (HT-29, p21 Waf1/Cip1: P=0.007; cyclin E2: P=0.008; cyclin D3: P=0.03; CDK9: P=0.01). (D) Comparison of the effect of the SNORD93 -overexpression vector and the control pGPU6-NC vector on apoptosis in CRC cell lines via flow cytometry. (E) Western blot profiling of apoptosis markers in SNORD93 -overexpressing CRC cells (HCT-15, caspase 8: P=0.044; caspase 3: P=0.044; caspase 7: P=0.006; Bim: P=0.01) (HT-29, caspase 8: P=0.01; caspase 3: P=0.02; caspase 7: P=0.008; Bim: P=0.002). (F) Western blot profiling of necroptosis markers in SNORD93 -overexpressing CRC cells <t>(HCT-15,</t> <t>p-RIP:</t> P=0.02; RIP: P=0.97; <t>p-MLKL:</t> P=0.04; MLKL: P=0.27) (HT-29, p-RIP: P=0.04; RIP: P=0.14; p-MLKL: P=0.01; MLKL: P=0.16). Data are presented as mean ± SD (n=3). ns, P>0.05; *, P<0.05; **, P<0.01. CRC, colorectal cancer; MLKL, mixed lineage kinase domain-like protein; NC, negative control; p-MLKL, phosphorylated MLKL; p-RIP, phosphorylated RIP; PI, propidium iodide; RIP, receptor-interacting protein; SD, standard deviation.
Phosphorylated Mixed Lineage Kinase Domain Like Protein P Mlkl Antibodies, supplied by Affinity Biosciences, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/protein+kinase+domain/anti+mlkl+p/pm40973012-60-10-21
Average 86 stars, based on 1 article reviews
phosphorylated mixed lineage kinase domain like protein p mlkl antibodies - by Bioz Stars, 2026-09
86/100 stars
  Buy from Supplier
phospho mixed lineage kinase domain like protein  (Cell Signaling Technology Inc)
86
Cell Signaling Technology Inc phospho mixed lineage kinase domain like protein
SNORD93 inhibited the proliferation of CRC. (A,B) Comparison of the effect of SNORD93 -overexpression vector and control pGPU6-NC vector on the cell cycle of CRC cell lines via flow cytometry (HCT-15: P=0.001; HT-29: P=0.048). (C) Western blot profiling of cell cycle regulators in SNORD93 -overexpressing CRC cells (HCT-15, p21 Waf1/Cip1: P=0.004; cyclin E2: P=0.047; cyclin D3: P=0.04; CDK9: P=0.03) (HT-29, p21 Waf1/Cip1: P=0.007; cyclin E2: P=0.008; cyclin D3: P=0.03; CDK9: P=0.01). (D) Comparison of the effect of the SNORD93 -overexpression vector and the control pGPU6-NC vector on apoptosis in CRC cell lines via flow cytometry. (E) Western blot profiling of apoptosis markers in SNORD93 -overexpressing CRC cells (HCT-15, caspase 8: P=0.044; caspase 3: P=0.044; caspase 7: P=0.006; Bim: P=0.01) (HT-29, caspase 8: P=0.01; caspase 3: P=0.02; caspase 7: P=0.008; Bim: P=0.002). (F) Western blot profiling of necroptosis markers in SNORD93 -overexpressing CRC cells <t>(HCT-15,</t> <t>p-RIP:</t> P=0.02; RIP: P=0.97; <t>p-MLKL:</t> P=0.04; MLKL: P=0.27) (HT-29, p-RIP: P=0.04; RIP: P=0.14; p-MLKL: P=0.01; MLKL: P=0.16). Data are presented as mean ± SD (n=3). ns, P>0.05; *, P<0.05; **, P<0.01. CRC, colorectal cancer; MLKL, mixed lineage kinase domain-like protein; NC, negative control; p-MLKL, phosphorylated MLKL; p-RIP, phosphorylated RIP; PI, propidium iodide; RIP, receptor-interacting protein; SD, standard deviation.
Phospho Mixed Lineage Kinase Domain Like Protein, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/protein+kinase+domain/10__1097_slash_cm9__0000000000003634-50-15-6
Average 86 stars, based on 1 article reviews
phospho mixed lineage kinase domain like protein - by Bioz Stars, 2026-09
86/100 stars
  Buy from Supplier
recombinant human epha2 kinase domain protein  (Eurofins)
90
Eurofins recombinant human epha2 kinase domain protein
SNORD93 inhibited the proliferation of CRC. (A,B) Comparison of the effect of SNORD93 -overexpression vector and control pGPU6-NC vector on the cell cycle of CRC cell lines via flow cytometry (HCT-15: P=0.001; HT-29: P=0.048). (C) Western blot profiling of cell cycle regulators in SNORD93 -overexpressing CRC cells (HCT-15, p21 Waf1/Cip1: P=0.004; cyclin E2: P=0.047; cyclin D3: P=0.04; CDK9: P=0.03) (HT-29, p21 Waf1/Cip1: P=0.007; cyclin E2: P=0.008; cyclin D3: P=0.03; CDK9: P=0.01). (D) Comparison of the effect of the SNORD93 -overexpression vector and the control pGPU6-NC vector on apoptosis in CRC cell lines via flow cytometry. (E) Western blot profiling of apoptosis markers in SNORD93 -overexpressing CRC cells (HCT-15, caspase 8: P=0.044; caspase 3: P=0.044; caspase 7: P=0.006; Bim: P=0.01) (HT-29, caspase 8: P=0.01; caspase 3: P=0.02; caspase 7: P=0.008; Bim: P=0.002). (F) Western blot profiling of necroptosis markers in SNORD93 -overexpressing CRC cells <t>(HCT-15,</t> <t>p-RIP:</t> P=0.02; RIP: P=0.97; <t>p-MLKL:</t> P=0.04; MLKL: P=0.27) (HT-29, p-RIP: P=0.04; RIP: P=0.14; p-MLKL: P=0.01; MLKL: P=0.16). Data are presented as mean ± SD (n=3). ns, P>0.05; *, P<0.05; **, P<0.01. CRC, colorectal cancer; MLKL, mixed lineage kinase domain-like protein; NC, negative control; p-MLKL, phosphorylated MLKL; p-RIP, phosphorylated RIP; PI, propidium iodide; RIP, receptor-interacting protein; SD, standard deviation.
Recombinant Human Epha2 Kinase Domain Protein, supplied by Eurofins, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/protein+kinase+domain/eph+a2/pmc11087803__pnas__2322934121__sapp-130-14-21
Average 90 stars, based on 1 article reviews
recombinant human epha2 kinase domain protein - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier
human ddr1 extracellular domain ecd protein  (Sino Biological)
93
Sino Biological human ddr1 extracellular domain ecd protein
SNORD93 inhibited the proliferation of CRC. (A,B) Comparison of the effect of SNORD93 -overexpression vector and control pGPU6-NC vector on the cell cycle of CRC cell lines via flow cytometry (HCT-15: P=0.001; HT-29: P=0.048). (C) Western blot profiling of cell cycle regulators in SNORD93 -overexpressing CRC cells (HCT-15, p21 Waf1/Cip1: P=0.004; cyclin E2: P=0.047; cyclin D3: P=0.04; CDK9: P=0.03) (HT-29, p21 Waf1/Cip1: P=0.007; cyclin E2: P=0.008; cyclin D3: P=0.03; CDK9: P=0.01). (D) Comparison of the effect of the SNORD93 -overexpression vector and the control pGPU6-NC vector on apoptosis in CRC cell lines via flow cytometry. (E) Western blot profiling of apoptosis markers in SNORD93 -overexpressing CRC cells (HCT-15, caspase 8: P=0.044; caspase 3: P=0.044; caspase 7: P=0.006; Bim: P=0.01) (HT-29, caspase 8: P=0.01; caspase 3: P=0.02; caspase 7: P=0.008; Bim: P=0.002). (F) Western blot profiling of necroptosis markers in SNORD93 -overexpressing CRC cells <t>(HCT-15,</t> <t>p-RIP:</t> P=0.02; RIP: P=0.97; <t>p-MLKL:</t> P=0.04; MLKL: P=0.27) (HT-29, p-RIP: P=0.04; RIP: P=0.14; p-MLKL: P=0.01; MLKL: P=0.16). Data are presented as mean ± SD (n=3). ns, P>0.05; *, P<0.05; **, P<0.01. CRC, colorectal cancer; MLKL, mixed lineage kinase domain-like protein; NC, negative control; p-MLKL, phosphorylated MLKL; p-RIP, phosphorylated RIP; PI, propidium iodide; RIP, receptor-interacting protein; SD, standard deviation.
Human Ddr1 Extracellular Domain Ecd Protein, supplied by Sino Biological, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/protein+kinase+domain/Human+DDR1+Kinase+%2F+MCK10+%2F+CD167+Protein/us12331130-1331-0-6
Average 93 stars, based on 1 article reviews
human ddr1 extracellular domain ecd protein - by Bioz Stars, 2026-09
93/100 stars
  Buy from Supplier

Image Search Results


SNORD93 inhibited the proliferation of CRC. (A,B) Comparison of the effect of SNORD93 -overexpression vector and control pGPU6-NC vector on the cell cycle of CRC cell lines via flow cytometry (HCT-15: P=0.001; HT-29: P=0.048). (C) Western blot profiling of cell cycle regulators in SNORD93 -overexpressing CRC cells (HCT-15, p21 Waf1/Cip1: P=0.004; cyclin E2: P=0.047; cyclin D3: P=0.04; CDK9: P=0.03) (HT-29, p21 Waf1/Cip1: P=0.007; cyclin E2: P=0.008; cyclin D3: P=0.03; CDK9: P=0.01). (D) Comparison of the effect of the SNORD93 -overexpression vector and the control pGPU6-NC vector on apoptosis in CRC cell lines via flow cytometry. (E) Western blot profiling of apoptosis markers in SNORD93 -overexpressing CRC cells (HCT-15, caspase 8: P=0.044; caspase 3: P=0.044; caspase 7: P=0.006; Bim: P=0.01) (HT-29, caspase 8: P=0.01; caspase 3: P=0.02; caspase 7: P=0.008; Bim: P=0.002). (F) Western blot profiling of necroptosis markers in SNORD93 -overexpressing CRC cells (HCT-15, p-RIP: P=0.02; RIP: P=0.97; p-MLKL: P=0.04; MLKL: P=0.27) (HT-29, p-RIP: P=0.04; RIP: P=0.14; p-MLKL: P=0.01; MLKL: P=0.16). Data are presented as mean ± SD (n=3). ns, P>0.05; *, P<0.05; **, P<0.01. CRC, colorectal cancer; MLKL, mixed lineage kinase domain-like protein; NC, negative control; p-MLKL, phosphorylated MLKL; p-RIP, phosphorylated RIP; PI, propidium iodide; RIP, receptor-interacting protein; SD, standard deviation.

Journal: Translational Cancer Research

Article Title: SNORD93 suppresses colorectal cancer progression by inducing G0/G1 arrest and apoptosis

doi: 10.21037/tcr-2025-1236

Figure Lengend Snippet: SNORD93 inhibited the proliferation of CRC. (A,B) Comparison of the effect of SNORD93 -overexpression vector and control pGPU6-NC vector on the cell cycle of CRC cell lines via flow cytometry (HCT-15: P=0.001; HT-29: P=0.048). (C) Western blot profiling of cell cycle regulators in SNORD93 -overexpressing CRC cells (HCT-15, p21 Waf1/Cip1: P=0.004; cyclin E2: P=0.047; cyclin D3: P=0.04; CDK9: P=0.03) (HT-29, p21 Waf1/Cip1: P=0.007; cyclin E2: P=0.008; cyclin D3: P=0.03; CDK9: P=0.01). (D) Comparison of the effect of the SNORD93 -overexpression vector and the control pGPU6-NC vector on apoptosis in CRC cell lines via flow cytometry. (E) Western blot profiling of apoptosis markers in SNORD93 -overexpressing CRC cells (HCT-15, caspase 8: P=0.044; caspase 3: P=0.044; caspase 7: P=0.006; Bim: P=0.01) (HT-29, caspase 8: P=0.01; caspase 3: P=0.02; caspase 7: P=0.008; Bim: P=0.002). (F) Western blot profiling of necroptosis markers in SNORD93 -overexpressing CRC cells (HCT-15, p-RIP: P=0.02; RIP: P=0.97; p-MLKL: P=0.04; MLKL: P=0.27) (HT-29, p-RIP: P=0.04; RIP: P=0.14; p-MLKL: P=0.01; MLKL: P=0.16). Data are presented as mean ± SD (n=3). ns, P>0.05; *, P<0.05; **, P<0.01. CRC, colorectal cancer; MLKL, mixed lineage kinase domain-like protein; NC, negative control; p-MLKL, phosphorylated MLKL; p-RIP, phosphorylated RIP; PI, propidium iodide; RIP, receptor-interacting protein; SD, standard deviation.

Article Snippet: Following this step, the membranes were blocked with 5% nonfat milk in Tris-buffered saline containing Tween-20 (TBST) for 2 hours at room temperature, which was followed by overnight incubation at 4 °C with the following primary antibodies: p21 [cat. No. 2947T; Cell Signaling Technology (CST), Danvers, MA, USA], cyclin D3 (cat. No. 2936T; CST), cyclin E2 (cat. No. 4132P; CST), CDK9 (cat. No. 2316P; CST), caspase 3 (cat. No. 14220T; CST), caspase 7 (cat. No. 12827T; CST), caspase 8 (cat. No. 4790T; CST), Bim (cat. No. 2933P; CST), receptor-interacting protein (RIP) (cat. No. 3493T; CST), phosphorylated RIP (p-RIP) (cat. No. 65746T; CST), mixed lineage kinase domain-like protein (MLKL) (cat. No. 14993T; CST), phosphorylated MLKL (p-MLKL) (cat. No. 91689T; CST), E-cadherin (cat. No. 3195T; CST), and β-catenin (cat. No. 8480T; CST). β-actin (cat. No. 3700; CST) and GAPDH (cat. No. 60004-1-Ig; Proteintech, Rosemont, IL, USA) were used as the reference proteins.

Techniques: Comparison, Over Expression, Plasmid Preparation, Control, Flow Cytometry, Western Blot, Negative Control, Standard Deviation